myrTissue-Cardio WT

myrTissue-Cardio WT

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€1.400,00
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€1.400,00
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human Engineered Heart Muscle from W001 wild type line; live.

myrTissues are macroscale human tissues to be used in drug discovery and development.

myriamed offers engineered macroscale tissues for advanced screens and target validation. myrTissues are shipped at ambient temperature for immediate use after 24h recovery in appropriate culture medium at 37° C. Each released batch of myrTissue comes with a Certificate of Analysis. Please contact us for details.

myrTissue-Cardio is engineered myocardium constructed from human iPSC derived cardiomyocytes and fibroblasts.

The major difference between myrTissue-Cardio and other approaches is the morphological maturity of myrTissue.

The tissues show important structural and functional properties of postnatal myocardium, including: specifically aligned sarcomeres, increasingly physiologically relevant resting membrane potentials and synchronized, rhythmic contractions. This functional and structural integrity is maintained for weeks.

 

Amount/Unit: 1 Tissue / 5 Tissues / 12 Tissues

Shipment Temperature: Room Temperature

Storage at End-user: 37° C

Order related manufacturing: Lead time 6-8 weeks

For more information see also Tiburcy et al. “Defined engineered human myocardium with advanced maturation for applications in heart failure modeling and repair.” Circulation vol. 135,19 (2017): 1832-1847. doi:10.1161/CIRCULATIONAHA.116.024145