myrTissue-Skeletal WT

myrTissue-Skeletal WT

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€1.400,00
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human Engineered Skeletal Muscle from W001 wild type line; live

myrTissues are macroscale human tissues to be used in drug discovery and development.

myriamed offers engineered macroscale tissues for advanced screens and target validation. myrTissues are shipped at ambient temperature for immediate use after 24h recovery in appropriate culture medium at 37° C. Each released batch of myrTissue comes with a Certificate of Analysis. Please contact us for details.

myrTissue-Skeletal is engineered skeletal muscle of hypaxial origin constructed from human iPSC derived myoblasts.

Tissue engineered muscle exhibits organotypic maturation and function, advanced by thyroid hormone. Regenerative competence can be shown in a cardiotoxin injury model with evidence of satellite cell activation as underlying mechanism. myrTissue-Skeletal is a hypaxial muscle model with canonical properties of bona fide skeletal muscle in vivo to study muscle development, maturation, disease, and repair.

 

Amount/Unit: 1 Tissue / 5 Tissues / 12 Tissues

Shipment Temperature: Room Temperature

Storage at End-user: 37° C

Order related manufacturing: Lead time 7-11 weeks

For more information see also Shahriyari et al. “Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity.” bioRxiv preprint. doi: https://doi.org/10.1101/2021.07.12.452030